Tilidine in focus: What is tilidine and how does it work?

Tilidine in focus: What is tilidine and how does it work?

Tilidine in focus: What is tilidine and how does it work?

Introduction

Tilidine is a strong pain reliever used to treat moderate to severe pain. It belongs to the group of opioids and is available in various dosage forms such as tablets, drops or injection solutions. In this article, we'll take a closer look at tilidine, explain how it works, and address frequently asked questions.

What is tilidine?

Tilidine is a synthetic opioid used to treat pain. It was first developed in the 1960s and has been a widespread and commonly used medication ever since. It is also offered in combination with the opioid antagonist naloxone to prevent abuse.

How is Tilidine used?

Tilidine is usually taken orally, either in the form of tablets or drops. If necessary, it can also be given as an injection. The dosage depends on the severity of the pain and the individual reaction of the patient. It is important to adhere to the dosage prescribed by your doctor and not to stop treatment or change the dosage yourself.

How does tilidine work?

Tilidine binds to opioid receptors in the brain and spinal cord, resulting in pain relief. It works by activating the μ-opioid receptor, which is responsible for pain perception, reward and breathing regulation. In addition, tilidine also increases the release of neurotransmitters such as dopamine and blocks the uptake of serotonin and norepinephrine. This helps improve mood and general well-being.

What side effects does tilidine have?

As with all strong painkillers, Tilidine can cause side effects. The most common side effects include drowsiness, dizziness, nausea, vomiting and constipation. Long-term use of tilidine may cause physical dependence, and sudden discontinuation of the medication may cause withdrawal symptoms. It is important to discuss possible side effects with a doctor and be closely monitored.

Are there risks and contraindications when using tilidine?

Tilidine is contraindicated in people with an allergy to the drug or other opioids, people with breathing problems such as asthma or COPD, people with severe liver or kidney impairment, and patients taking monoamine oxidase inhibitors (MAOIs). Tilidine should also be used with caution during pregnancy and breastfeeding as it may affect the unborn child or breastfed baby.

How long does tilidine last?

The duration of action of tilidine depends on the dosage form. Tilidine in tablet form usually works for around four to six hours, while the extended-release tablets and drops have a longer effect of around eight to twelve hours. It is important to adhere to the intake intervals and not to increase the dosage on your own in order to avoid overdoses.

How can Tilidine reduce side effects?

Tilidine side effects can be minimized by adhering to the prescribed dosage and regular medical monitoring. Adequate fluid intake and a diet high in fiber can help reduce constipation. However, if side effects become severe or intolerable, a doctor should be consulted to explore alternative treatment options.

Can tilidine be addictive?

Yes, tilidine can cause physical dependence due to its opioid properties. With prolonged and/or high-dose use, tolerance development and a withdrawal syndrome may occur. Therefore, it is important to reduce the dosage under medical supervision and not to stop taking the medication abruptly.

Conclusion

Tilidine is a strong pain reliever used to treat moderate to severe pain. It binds to opioid receptors in the brain and spinal cord and results in pain relief. As with all medications, side effects can occur and there is a risk of physical dependence. The use of Tilidine requires careful medical supervision and adherence to the prescribed dosage.